Magnesium Orotate is an organic compound formed by the coordination bonding of the mineral magnesium with orotic acid. Orotic acid, being a precursor in pyrimidine nucleotide biosynthesis, is thought to potentially facilitate the targeted transport and retention of magnesium ions within cells, particularly in tissues with high energy demands like the myocardium, thereby supporting magnesium's bioavailability.
| Product Name | Magnesium Orotate |
| Appearance | White or off white powder |
| CAS No. | 34717-03-8 |
| Molecular Formula | C10H4MgN4O8 |
| Molecular Weight | 332.47 |
This ingredient is utilized in the dietary supplement arena, aiming to simultaneously support cardiovascular wellness, energy metabolism, and electrolyte balance. It is suitable for individuals focused on cardiac function, athletic performance, and magnesium nutritional status.
Magnesium orotate is a coordination complex where magnesium ions are chelated by orotic acid, leveraging the vitamin B13 precursor's role in nucleotide synthesis to enhance cellular energy production. The compound's unique pharmacokinetics involve facilitated absorption through shared transporters with pyrimidines, achieving higher myocardial magnesium concentrations compared to inorganic salts.
Clinical studies demonstrate benefits in congestive heart failure through improved ejection fraction and reduced angina frequency, while magnesium's membrane-stabilizing properties counteract excitability in neuronal and smooth muscle tissues. It is positioned as a preferred formulation for long-term supplementation without significant gastrointestinal distress.
What makes Magnesium Orotate different from other magnesium salts?
Magnesium Orotate is chelated with orotic acid, which acts as a transporter to deliver magnesium directly into the cells, particularly heart and muscle tissues, improving bioavailability.
What is the purity of your Magnesium Orotate powder?
Our product maintains a high purity level of ≥ 99.0%, meeting pharmaceutical and dietary supplement standards.
Does it cause gastrointestinal distress?
Unlike some inorganic magnesium forms, Magnesium Orotate is generally well-tolerated and is less likely to cause significant gastrointestinal discomfort when taken at recommended dosages.
Is this product suitable for athletes?
Yes, it is highly suitable for athletes as it supports energy metabolism, ATP regeneration, and electrolyte balance during intense physical activity.
What is the recommended shelf life and storage?
The shelf life is 2 years. It should be stored in a cool, dry place away from direct sunlight and moisture to maintain its stability.
What certifications does your manufacturing process hold?
The production process complies with GMP, ISO 9001, and HSE standards, ensuring high quality and safety for pharmaceutical use.